Tumor necrosis factor receptor superfamily member 3 (LTBR) is a 435-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P36941.
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The mean pLDDT of this model is 66.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 32% |
| 70 to 90 | Confident: backbone generally right | 17% |
| 50 to 70 | Low: treat with caution | 15% |
| Below 50 | Very low: often disordered regions | 37% |
What pLDDT means and how to read it
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT (PubMed:24248355). Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)) (PubMed:24248355). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs
Self-associates; dimerization and trimerization are promoted by lymphotoxin (LTA(1)-LTB(2)) (PubMed:29507355). Associates with TRAF3 (PubMed:8663299). Associates with TRAF4 (PubMed:9626059). Associates with TRAF5 (PubMed:9511754). Interacts with Aedes aegypti lymphotoxin beta receptor inhibitor; the interaction reduces dimerization and trimerization of LTBR induced by lymphotoxin (LTA(1)-LTB(2))…
Membrane
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