P38968: Protein transport protein SEC31 (SEC31)

Protein transport protein SEC31 (SEC31) is a 1273-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P38968.

Gene
SEC31
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1273 residues
Mean pLDDT
69.7
Model
AF-P38968-F1 v6
Model created
1 Aug 2025
PDB structures
10

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Model confidence (pLDDT)

The mean pLDDT of this model is 69.7 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate37%
70 to 90Confident: backbone generally right23%
50 to 70Low: treat with caution6%
Below 50Very low: often disordered regions34%

What pLDDT means and how to read it

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Subunit structure

The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. SEC13 and SEC31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13. Interacts with EMP24, ERV25, SEC16 and SHR3

Subcellular location

Cytoplasmic vesicle, COPII-coated vesicle membrane, Endoplasmic reticulum membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2PM7X-ray2.35 ÅA/C=370-763
2PM6X-ray2.45 ÅA/C=370-763
2QTVX-ray2.5 ÅD=899-947
3MZLX-ray2.8 ÅB/D/F/H=370-746
2PM9X-ray3.3 ÅA=1-411
4BZJEM40.0 ÅA/C=1-1273
4BZKEM40.0 ÅA/C=1-1273
6ZG5EM40.0 ÅA/C=1-1273
6ZG6EM40.0 ÅA/C/E/G=1-1273
6ZL0EM40.0 ÅA/C=1-1273

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