Aurora kinase (IPL1) is a 367-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P38991.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 76.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 60% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 25% |
What pLDDT means and how to read it
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis (PubMed:11853667, PubMed:12408861). Has a role in error-correction of aberrent kinetochore-microtubule attachments to ensure that sister kinetochores become bioriented and connect to opposite poles by promoting spindle assembly checkpoint signaling (PubMed:11724818, PubMed:11853667, PubMed:12408861). Acts in opposition to the phosphatase PP1 (PubMed:10975519). Not required for kinetochore detachment from microtubules during replication of centromeric DNA (PubMed:18079178). Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis…
Component of the CPC complex at least composed of IPL1, BIR1 and SLI15
Nucleus, Cytoplasm, cytoskeleton, spindle, Chromosome, centromere, kinetochore
UniProt lists no experimental PDB structure for this protein, so the AlphaFold prediction is the main 3D model available.
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.