Non-toxic nonhemagglutinin type E (ent-120) is a 1162-residue protein from Clostridium botulinum. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P46082.
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The mean pLDDT of this model is 93.0 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Assembles with botulinum neurotoxin type E (BoNT/E) and protects it against pH-mediated inactivation or protease activity at pH 2.6 (the pH of the animal gastrointestinal tract) but not at pH 6.0 (By similarity). The non-toxic component is necessary to maintain toxicity
Forms a highly interlocked heterodimer with botulinum neurotoxin type E at pH 6.0 but not at pH 7.5 (By similarity)
Compare the prediction with experimentally determined structures of the same protein:
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