Troponin T, cardiac muscle (Tnnt2) is a 301-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P50752.
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The mean pLDDT of this model is 74.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 42% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 29% |
| Below 50 | Very low: often disordered regions | 16% |
What pLDDT means and how to read it
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9E2E | EM | 4.0 Å | K/P=1-301 |
| 9MOM | EM | 5.1 Å | J/K=1-301 |
| 9MO7 | EM | 5.2 Å | I/J=1-301 |
| 9MO8 | EM | 5.2 Å | J/K=1-301 |
| 9MOL | EM | 5.2 Å | J/K=1-301 |
| 9MON | EM | 5.2 Å | J/K=1-301 |
| 9MO4 | EM | 5.3 Å | I/J=1-301 |
| 9MO5 | EM | 5.3 Å | I/J=1-301 |
| 9MO6 | EM | 5.3 Å | I/J=1-301 |
| 9MOI | EM | 5.4 Å | I/J=1-301 |
| 9MOK | EM | 5.6 Å | J/K=1-301 |
| 6KLT | EM | 12.0 Å | B=212-282 |
| 6KLU | EM | 12.0 Å | B=212-285 |
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