P50995: Annexin A11 (ANXA11)

Annexin A11 (ANXA11) is a 505-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P50995.

Gene
ANXA11
Organism
Homo sapiens
Length
505 residues
Mean pLDDT
75.8
Model
AF-P50995-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 75.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate60%
70 to 90Confident: backbone generally right3%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions34%

What pLDDT means and how to read it

Function

Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis

Subunit structure

Interacts with S100A6 (PubMed:28469040). Interacts with PDCD6 in a calcium-dependent manner. Interacts with KIF23 during cytokinesis

Subcellular location

Cytoplasm, Melanosome, Nucleus envelope, Nucleus, nucleoplasm, Cytoplasm, cytoskeleton, spindle

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9FOREM2.75 ÅB/D/F/H/p=39-74
9FOFEM2.9 ÅB/D/F/H/J/r=39-74

More AlphaFold highlights

About this viewer

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