Tubulin gamma chain (TUB4) is a 473-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P53378.
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The mean pLDDT of this model is 79.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 58% |
| 50 to 70 | Low: treat with caution | 15% |
| Below 50 | Very low: often disordered regions | 7% |
What pLDDT means and how to read it
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. TUB4 is an important spindle pole body component that organizes both cytoplasmic and nuclear microtubule arrays
Interacts with SPC72, SPC97 and SPC98
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7M2W | EM | 3.0 Å | A/B/C/D=1-473 |
| 7M2X | EM | 3.6 Å | A/B=1-473 |
| 7M2Z | EM | 3.7 Å | A/B=1-473 |
| 7M2Y | EM | 4.03 Å | A/B=1-473 |
| 5FLZ | EM | 6.9 Å | C/D=1-473 |
| 5FM1 | EM | 8.0 Å | C/D=1-473 |
| 8QV3 | EM | 8.2 Å | c/d=1-473 |
| 8QV2 | EM | 9.2 Å | a/b/c/d/e/f/g/h/i/j/k/l/m/n=1-473 |
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