P53969: Sorting assembly machinery 50 kDa subunit (SAM50)

Sorting assembly machinery 50 kDa subunit (SAM50) is a 484-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P53969.

Gene
SAM50
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
484 residues
Mean pLDDT
85.9
Model
AF-P53969-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 85.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate61%
70 to 90Confident: backbone generally right26%
50 to 70Low: treat with caution8%
Below 50Very low: often disordered regions5%

What pLDDT means and how to read it

Function

Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex

Subunit structure

Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which at least consists of SAM35, SAM37 and SAM50 (PubMed:14570913, PubMed:14685243, PubMed:15590639). Associates with the mitochondrial contact site and cristae organizing system (MICOS) complex (also known as MINOS or MitOS complex) (By similarity)

Subcellular location

Mitochondrion outer membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7E4HEM3.01 ÅA=2-484
7E4IEM3.05 ÅA=2-484
7VKUEM3.2 ÅA=1-484

More AlphaFold highlights

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