Large ribosomal subunit protein uL2 (rplB) is a 273-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P60422.
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The mean pLDDT of this model is 95.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 96% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Component of the large ribosomal subunit (PubMed:3298242, PubMed:8722025). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:8722025). One of the primary rRNA binding proteins (PubMed:3298242). Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation (PubMed:8722025). It has been suggested to have peptidyltransferase activity; this is highly controversial (Probable)
Part of the 50S ribosomal subunit (PubMed:10094780, PubMed:10756104, PubMed:11114255, PubMed:12809609, PubMed:16272117, PubMed:24844575, PubMed:25310980, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:3298242, PubMed:7556101, PubMed:8722025, PubMed:9298644, Ref.4). Forms a bridge to the 30S subunit in the 70S ribosome, contacting the 16S rRNA (PubMed:12809609). Interacts weakly with…
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8B0X | EM | 1.55 Å | c=1-273 |
| 9Q87 | EM | 1.55 Å | c=1-273 |
| 8CGK | EM | 1.64 Å | c=1-273 |
| 8CGV | EM | 1.66 Å | c=1-273 |
| 8CEU | EM | 1.83 Å | c=1-273 |
| 8FTO | EM | 1.85 Å | c=1-273 |
| 8CAM | EM | 1.86 Å | c=1-273 |
| 9GHE | EM | 1.87 Å | c=1-273 |
| 8E30 | EM | 1.91 Å | K=2-272 |
| 9D89 | EM | 1.95 Å | F=1-273 |
| 8AYE | EM | 1.96 Å | c=1-273 |
| 7K00 | EM | 1.98 Å | c=1-273 |
| 8CGD | EM | 1.98 Å | c=1-273 |
| 8E3O | EM | 1.99 Å | K=2-272 |
| 8QOA | EM | 2.0 Å | c=1-273 |
| 8G6W | EM | 2.02 Å | c=1-273 |
| 8BIL | EM | 2.04 Å | A=1-273 |
| 8BIM | EM | 2.04 Å | A=1-273 |
| 8E49 | EM | 2.05 Å | K=2-272 |
| 8E43 | EM | 2.09 Å | K=2-272 |
Showing 20 of 596 experimental structures (best resolution first).
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