Large ribosomal subunit protein uL3 (rplC) is a 209-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P60438.
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The mean pLDDT of this model is 97.0 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 98% |
| 70 to 90 | Confident: backbone generally right | 2% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
One of two assembly initiator proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Part of the 50S ribosomal subunit (PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:24844575, PubMed:25310980, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:365579). Forms a cluster with proteins L14 and L19. In pull-down experiments interacts with CedA (PubMed:28818726)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8B0X | EM | 1.55 Å | d=1-209 |
| 9Q87 | EM | 1.55 Å | d=1-209 |
| 8CGK | EM | 1.64 Å | d=1-209 |
| 8CGV | EM | 1.66 Å | d=1-209 |
| 8CEU | EM | 1.83 Å | d=1-209 |
| 8FTO | EM | 1.85 Å | d=1-209 |
| 8CAM | EM | 1.86 Å | d=1-209 |
| 9GHE | EM | 1.87 Å | d=1-209 |
| 8E30 | EM | 1.91 Å | N=1-209 |
| 9D89 | EM | 1.95 Å | G=1-209 |
| 8AYE | EM | 1.96 Å | d=1-209 |
| 7K00 | EM | 1.98 Å | d=1-209 |
| 8CGD | EM | 1.98 Å | d=1-209 |
| 8E3O | EM | 1.99 Å | N=1-209 |
| 8QOA | EM | 2.0 Å | d=1-209 |
| 8G6W | EM | 2.02 Å | d=1-209 |
| 8BIL | EM | 2.04 Å | B=1-209 |
| 8BIM | EM | 2.04 Å | B=1-209 |
| 8E49 | EM | 2.05 Å | N=1-209 |
| 8E43 | EM | 2.09 Å | N=1-209 |
Showing 20 of 617 experimental structures (best resolution first).
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