P60723: Large ribosomal subunit protein uL4 (rplD)

Large ribosomal subunit protein uL4 (rplD) is a 201-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P60723.

Gene

rplD

Organism

Escherichia coli (strain K12)

Length

201 residues

Mean pLDDT

94.3

Model

AF-P60723-F1 v6

Model created

1 Aug 2025

PDB structures

626

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Model confidence (pLDDT)

The mean pLDDT of this model is 94.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

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Function

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA (PubMed:3298242). It is important during the early stages of 50S assembly (PubMed:3298242). It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (PubMed:6170935, PubMed:7556101)

Subunit structure

Part of the 50S ribosomal subunit (PubMed:10094780, PubMed:11511371, PubMed:12809609, PubMed:16272117, PubMed:24844575, PubMed:25310980, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:3298242, PubMed:34403461, PubMed:34504068, PubMed:7556101, Ref.1). In TnaC-stalled ribosomes forms part of the binding pocket for L-Trp with the leader peptide and uL22 (PubMed:34403461, PubMed:34504068)

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

Showing 20 of 626 experimental structures (best resolution first).

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