cAMP-dependent protein kinase inhibitor alpha (Pkia) is a 76-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P63249.
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The mean pLDDT of this model is 63.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 4% |
| 70 to 90 | Confident: backbone generally right | 36% |
| 50 to 70 | Low: treat with caution | 41% |
| Below 50 | Very low: often disordered regions | 20% |
What pLDDT means and how to read it
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1Q8U | X-ray | 1.9 Å | B=6-25 |
| 1L3R | X-ray | 2.0 Å | I=6-25 |
| 1YDS | X-ray | 2.2 Å | I=6-25 |
| 1Q62 | X-ray | 2.3 Å | I=6-25 |
| 1SVH | X-ray | 2.3 Å | B=6-25 |
| 1YDT | X-ray | 2.3 Å | I=6-25 |
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