Histone H3.2 (H3C2) is a 136-residue protein from Zea mays. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P69246.
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The mean pLDDT of this model is 85.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 68% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 26% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Nucleus, Chromosome
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7EF0 | X-ray | 1.5 Å | P=2-20 |
| 7EF1 | X-ray | 1.9 Å | P/Q=2-11 |
| 7EF2 | X-ray | 2.0 Å | P/Q=2-11 |
| 7EF3 | X-ray | 2.1 Å | P/Q=2-11 |
| 7UBU | X-ray | 2.39 Å | P/Q=2-33 |
| 9MVY | X-ray | 2.71 Å | G/H/I/P=2-33 |
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