P78318: Immunoglobulin-binding protein 1 (IGBP1)

Immunoglobulin-binding protein 1 (IGBP1) is a 339-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P78318.

Gene
IGBP1
Organism
Homo sapiens
Length
339 residues
Mean pLDDT
81.8
Model
AF-P78318-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 81.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate50%
70 to 90Confident: backbone generally right27%
50 to 70Low: treat with caution15%
Below 50Very low: often disordered regions8%

What pLDDT means and how to read it

Function

Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits

Subunit structure

Interacts with partially folded PPP2CA, but not with the fully active protein. Interacts with PPP2CB, and with PP4 and PP6. Interacts with MID1 and MID2. Interacts with ubiquitin

Subcellular location

Cytoplasm

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4IYPX-ray2.8 ÅA=2-234

More AlphaFold highlights

About this viewer

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