Muscarinic toxin 3 is a 65-residue protein from Dendroaspis angusticeps. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P81031.
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The mean pLDDT of this model is 94.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 94% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Potent antagonist (IC(50)=1-10 nM) of M4 (CHRM4) muscarinic receptors (PubMed:8154745, PubMed:24793485, PubMed:21557730), and CHRM1, ADRA1A (PubMed:8154745), ADRA2A and ADRA2C adrenergic receptors. Also antagonises ADRA1B and ADRA1D adrenergic receptors with a 10-times lower affinity (PubMed:24793485)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
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