Q01939: 26S proteasome regulatory subunit 8 homolog (RPT6)

26S proteasome regulatory subunit 8 homolog (RPT6) is a 405-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q01939.

Gene: RPT6
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length: 405 residues
Mean pLDDT: 81.6
Model: AF-Q01939-F1 v6
Model created: 1 Aug 2025
PDB structures: 31

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 81.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT band	Meaning	Share of residues
Above 90	Very high: backbone and side chains are usually accurate	22%
70 to 90	Confident: backbone generally right	64%
50 to 70	Low: treat with caution	10%
Below 50	Very low: often disordered regions	4%

What pLDDT means and how to read it

Function

The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity)

Subunit structure

May form a homodimer or a heterodimer with a related family member. Interacts with OLA1, TMA17, and UBR1

Subcellular location

Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB ID	Method	Resolution	Chains and residues
9CGC	EM	3.61 Å	J=1-405
6J2Q	EM	3.8 Å	J=1-405
6J2X	EM	3.8 Å	J=1-405
5MP9	EM	4.1 Å	J=1-405
6FVT	EM	4.1 Å	J=1-405
6EF3	EM	4.17 Å	J=1-405
5WVK	EM	4.2 Å	J=1-405
6EF2	EM	4.27 Å	J=144-405
6EF0	EM	4.43 Å	J=130-405
5MPA	EM	4.5 Å	J=1-405
6FVU	EM	4.5 Å	J=1-405
6FVW	EM	4.5 Å	J=3-405
6J30	EM	4.5 Å	J=1-405
3JCP	EM	4.6 Å	J=1-405
6EF1	EM	4.73 Å	J=133-405
3JCO	EM	4.8 Å	J=1-405
6FVX	EM	4.9 Å	J=1-405
6FVV	EM	5.4 Å	J=1-405
7QO5	EM	6.0 Å	J=1-405
6FVY	EM	6.1 Å	J=1-405

Showing 20 of 31 experimental structures (best resolution first).

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.