Q02208: Topoisomerase 1-associated factor 2 (TOF2)

Topoisomerase 1-associated factor 2 (TOF2) is a 771-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q02208.

Gene
TOF2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
771 residues
Mean pLDDT
52.1
Model
AF-Q02208-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 52.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate9%
70 to 90Confident: backbone generally right6%
50 to 70Low: treat with caution18%
Below 50Very low: often disordered regions67%

What pLDDT means and how to read it

Subunit structure

Interacts with HPR1

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5V3NX-ray1.3 ÅB=384-398
5HOIX-ray3.3 ÅD/E/F=497-517

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