Q03124: Chromatin structure-remodeling complex subunit RSC9 (RSC9)

Chromatin structure-remodeling complex subunit RSC9 (RSC9) is a 581-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q03124.

Gene
RSC9
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
581 residues
Mean pLDDT
85.4
Model
AF-Q03124-F1 v6
Model created
1 Aug 2025
PDB structures
7

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Model confidence (pLDDT)

The mean pLDDT of this model is 85.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate68%
70 to 90Confident: backbone generally right13%
50 to 70Low: treat with caution13%
Below 50Very low: often disordered regions7%

What pLDDT means and how to read it

Function

Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning (PubMed:10025404, PubMed:10329629, PubMed:11931764, PubMed:12072455, PubMed:8980231). RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA (PubMed:10025404, PubMed:10329629). The reaction requires ATP and involves an activated RSC-nucleosome intermediate (PubMed:12183366). Remodeling reaction also involves DNA translocation, DNA twist and conformational change (PubMed:12183366). As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in…

Subunit structure

Component of the two forms of the RSC complex composed of at least either RSC1 or RSC2, and ARP7, ARP9, LDB7, NPL6, RSC3, RSC30, RSC4, RSC58, RSC6, RSC8, RSC9, SFH1, STH1, HTL1 and probably RTT102. The complexes interact with histone and histone variant components of centromeric chromatin

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6V8OEM3.07 ÅN=1-581
6K15EM3.4 ÅM=1-581
6KW3EM7.13 ÅM=1-581
6KW4EM7.55 ÅM=1-581
6KW5EM10.13 ÅM=1-581
6TDAEM15.0 ÅN=1-581
6V92EM20.0 ÅN=1-581

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