Vacuolar protein sorting-associated protein 72 (VPS72) is a 795-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q03388.
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The mean pLDDT of this model is 58.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 7% |
| 70 to 90 | Confident: backbone generally right | 27% |
| 50 to 70 | Low: treat with caution | 21% |
| Below 50 | Very low: often disordered regions | 46% |
What pLDDT means and how to read it
Participates in the catalytic exchange of histone H2A for the H2A variant HTZ1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes. Indirectly involved in vacuolar protein sorting
Belongs to the SWR1 complex at least composed of ACT1, ARP4, RVB1, RVB2, ARP6, YAF9, VPS71, VPS72, SWC3, SWC4, SWC5, SWR1 and HTZ1. Interacts with HTZ1
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9B1D | EM | 3.3 Å | B=1-795 |
| 8QYV | EM | 3.5 Å | Z=1-795 |
| 8QKU | EM | 3.8 Å | Z=195-623 |
| 8QZ0 | EM | 3.8 Å | Z=1-795 |
| 9B1E | EM | 4.4 Å | B=1-795 |
| 9FBW | EM | 4.4 Å | Z=1-795 |
| 8QKV | EM | 4.7 Å | Z=195-623 |
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