Q10059: Cell division control protein 12 (cdc12)

Cell division control protein 12 (cdc12) is a 1841-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q10059.

Gene
cdc12
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
1841 residues
Mean pLDDT
55.8
Model
AF-Q10059-F1 v6
Model created
1 Aug 2025
PDB structures
2

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 55.8 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate13%
70 to 90Confident: backbone generally right25%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions50%

What pLDDT means and how to read it

Function

Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends

Subunit structure

Interacts with profilin and actin at the FH1 and FH2 domains respectively

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8RTTEM3.56 ÅE/F=972-1390
8RTYEM6.25 ÅE/F=881-1390

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.