Q10109: Lap-Emerin-Man domain protein 2 (lem2)

Lap-Emerin-Man domain protein 2 (lem2) is a 688-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q10109.

Gene
lem2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
688 residues
Mean pLDDT
68.4
Model
AF-Q10109-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 68.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate29%
70 to 90Confident: backbone generally right26%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions33%

What pLDDT means and how to read it

Function

Nucleus inner membrane protein involved in meiosis (PubMed:20404563). Plays a role in regulating nuclear envelope (NE) morphology and nuclear integrity, particularly during spindle pole body (SPB) extrusion or insertion through the NE, and perhaps during karyokinesis (PubMed:28242692)

Subcellular location

Nucleus inner membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5YCAX-ray1.57 ÅC=261-279

More AlphaFold highlights

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