Q12176: Ribosome biogenesis protein MAK21 (MAK21)

Ribosome biogenesis protein MAK21 (MAK21) is a 1025-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12176.

Gene
MAK21
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1025 residues
Mean pLDDT
67.4
Model
AF-Q12176-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 67.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate17%
70 to 90Confident: backbone generally right40%
50 to 70Low: treat with caution14%
Below 50Very low: often disordered regions29%

What pLDDT means and how to read it

Function

Required for 60S ribosomal subunit synthesis

Subunit structure

Interacts with NOC2. Forms a nucleolar complex with NOC2 that binds to 90S and 66S pre-ribosomes

Subcellular location

Nucleus, nucleolus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9QJCEM3.2 Å5=1-1025
8E5TEM4.0 Å5=1-1025

More AlphaFold highlights

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