Structural maintenance of chromosomes protein 6 (SMC6) is a 1114-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12749.
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The mean pLDDT of this model is 79.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 26% |
| 70 to 90 | Confident: backbone generally right | 60% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 8% |
What pLDDT means and how to read it
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Probably plays a role in structure
Component of the Smc5-Smc6 complex which consists of KRE29, MMS21, NSE1, NSE3, NSE4, NSE5, SMC5 and SMC6
Nucleus, Chromosome
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8HQS | EM | 3.2 Å | B=1-1114 |
| 8T8E | EM | 3.3 Å | A=1-1114 |
| 7TVE | EM | 3.8 Å | D=1-1114 |
| 8T8F | EM | 4.8 Å | E=1-1114 |
| 8WJN | EM | 5.58 Å | B=1-1114 |
| 7YQH | EM | 5.6 Å | B=1-1114 |
| 8I4V | EM | 5.97 Å | B=1-1114 |
| 8I4W | EM | 6.01 Å | B=1-1114 |
| 8I21 | EM | 6.02 Å | B=1-1114 |
| 8WJO | EM | 6.04 Å | B=1-1114 |
| 8WJL | EM | 6.15 Å | B=1-1114 |
| 7YLM | EM | 6.17 Å | B=1-1114 |
| 8I4U | EM | 6.73 Å | B=1-1114 |
| 7QCD | EM | 8.0 Å | B=1-1114 |
| 8I4X | EM | 8.5 Å | B=1-1104 |
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