Aspartyl/asparaginyl beta-hydroxylase (ASPH) is a 758-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12797.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 71.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 55% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 37% |
What pLDDT means and how to read it
Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins
Monomer (By similarity). Isoform 8 interacts with ORAI1 and STIM1. Isoform 4 interacts with CASQ2
Endoplasmic reticulum membrane, Sarcoplasmic reticulum membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6YYX | X-ray | 1.53 Å | A=330-758 |
| 7YB9 | X-ray | 1.54 Å | A=329-758 |
| 9FVV | X-ray | 1.6 Å | A=330-758 |
| 6Q9F | X-ray | 1.63 Å | A=330-758 |
| 7BMI | X-ray | 1.66 Å | A=330-758 |
| 7YBB | X-ray | 1.68 Å | A=330-758 |
| 8RE5 | X-ray | 1.7 Å | A=315-758 |
| 9FVU | X-ray | 1.7 Å | A=1-758 |
| 7BMJ | X-ray | 1.75 Å | A/C=330-758 |
| 6YYV | X-ray | 1.77 Å | A=330-758 |
| 6Z6Q | X-ray | 1.81 Å | A=330-758 |
| 9HO2 | X-ray | 1.83 Å | A=331-758 |
| 7YBC | X-ray | 1.84 Å | A=330-758 |
| 8RE9 | X-ray | 1.84 Å | A=315-758 |
| 6Q9I | X-ray | 1.85 Å | A=330-758 |
| 8RE8 | X-ray | 1.85 Å | A=315-758 |
| 9HO1 | X-ray | 1.85 Å | A=330-758 |
| 7YBA | X-ray | 1.86 Å | A=330-758 |
| 7E6J | X-ray | 1.9 Å | A=330-758 |
| 9FVW | X-ray | 1.9 Å | A=330-758 |
Showing 20 of 43 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.