Q14320: Protein FAM50A (FAM50A)

Protein FAM50A (FAM50A) is a 339-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q14320.

Gene
FAM50A
Organism
Homo sapiens
Length
339 residues
Mean pLDDT
75.9
Model
AF-Q14320-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 75.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate26%
70 to 90Confident: backbone generally right43%
50 to 70Low: treat with caution18%
Below 50Very low: often disordered regions13%

What pLDDT means and how to read it

Function

Probably involved in the regulation of pre-mRNA splicing

Subunit structure

Interacts with EFTUD2, a component of the spliceosome U5 complex (PubMed:32703943). Interacts with DDX41, a component of the spliceosome C complex (PubMed:32703943)

Subcellular location

Nucleus

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8C6JEM2.8 ÅCF=1-339
9FMDEM3.3 Å50=1-339

More AlphaFold highlights

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