Q15013: MAD2L1-binding protein (MAD2L1BP)

MAD2L1-binding protein (MAD2L1BP) is a 274-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q15013.

Gene
MAD2L1BP
Organism
Homo sapiens
Length
274 residues
Mean pLDDT
80.0
Model
AF-Q15013-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 80.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate61%
70 to 90Confident: backbone generally right8%
50 to 70Low: treat with caution14%
Below 50Very low: often disordered regions17%

What pLDDT means and how to read it

Function

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex

Subunit structure

Interacts with MAD2L1

Subcellular location

Nucleus, Cytoplasm, cytoskeleton, spindle

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2QYFX-ray2.3 ÅB/D=36-274
6F0XEM4.6 ÅP=1-274

More AlphaFold highlights

About this viewer

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