Phosphoglucomutase-like protein 5 (PGM5) is a 567-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q15124.
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The mean pLDDT of this model is 96.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 96% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Component of adherens-type cell-cell and cell-matrix junctions (PubMed:8175905). Positively regulates maturation and alignment of myofibrils, also promotes organization of sarcomeres (By similarity). Has no phosphoglucomutase activity in vitro (PubMed:8175905)
Interacts with DMD/dystrophin; the interaction is direct (By similarity). Interacts with UTRN/utrophin (By similarity). Interacts (via N-terminus) with XIRP1 isoform B (XinB) or FLNC (via repeats 18 to 21); the interactions are competitive and do not form a ternary complex (By similarity)
Cell junction, adherens junction, Cytoplasm, cytoskeleton, Cell membrane, sarcolemma
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7U21 | X-ray | 1.9 Å | C/F=465-473 |
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