Q16348: Solute carrier family 15 member 2 (SLC15A2)

Solute carrier family 15 member 2 (SLC15A2) is a 729-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q16348.

Gene
SLC15A2
Organism
Homo sapiens
Length
729 residues
Mean pLDDT
84.1
Model
AF-Q16348-F1 v6
Model created
1 Aug 2025
PDB structures
3

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 84.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate46%
70 to 90Confident: backbone generally right42%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions8%

What pLDDT means and how to read it

Function

Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:16434549, PubMed:18367661, PubMed:7756356). Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1 (By similarity). In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate (PubMed:7756356). Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs (PubMed:16434549). Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Also able to transport carnosine (PubMed:31073693). Involved in…

Subunit structure

Interacts (via extracellular domain region) with trypsin

Subcellular location

Apical cell membrane, Cytoplasmic vesicle, phagosome membrane, Cell membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6EZIX-ray1.5 ÅB=720-729
9UDCEM3.38 ÅA=1-729
7PMYEM3.8 ÅA=1-729

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.