Q2I0M4: Leucine-rich repeat-containing protein 26 (LRRC26)

Leucine-rich repeat-containing protein 26 (LRRC26) is a 334-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q2I0M4.

Gene
LRRC26
Organism
Homo sapiens
Length
334 residues
Mean pLDDT
82.5
Model
AF-Q2I0M4-F1 v6
Model created
1 Aug 2025
PDB structures
7

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 82.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate57%
70 to 90Confident: backbone generally right20%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions12%

What pLDDT means and how to read it

Function

Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium

Subunit structure

Interacts with KCNMA1

Subcellular location

Cell membrane, Cytoplasm, cytoskeleton

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8VAZEM2.82 ÅE/F/G/H=1-334
7YO3EM3.1 ÅB=1-334
8VAVEM3.13 ÅE/F/G/H=1-334
7YNZEM3.5 ÅB/D/F/H=1-334
7YO0EM3.6 ÅB/D/F/H=1-334
7YO1EM3.6 ÅB/D/F/H=1-334
7YO4EM3.9 ÅB/D/F/H=1-334

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.