Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Lrfn1) is a 766-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q2WF71.
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The mean pLDDT of this model is 69.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 41% |
| 70 to 90 | Confident: backbone generally right | 17% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 34% |
What pLDDT means and how to read it
Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1
Can form heteromeric complexes with LRFN2, LRFN3, LRFN4 and LRFN5. Forms homomeric complexes, but not across cell junctions. Interacts with DLG4. Also interacts with DLG1, DLG2, and DLG3 (By similarity). Interacts with 2 AMPA receptor subunits GRIA1 and GRIA2 and NMDA receptor subunit GRIN1
Membrane, Synapse, Postsynaptic density membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5XWU | X-ray | 3.16 Å | B/D=32-390 |
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