Cilia- and flagella-associated protein 65 (Cfap65) is a 1847-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q3V0B4.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 72.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 11% |
| 70 to 90 | Confident: backbone generally right | 59% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 18% |
What pLDDT means and how to read it
Plays a role in flagellar formation and sperm motility (PubMed:31501240). Essential for acrosome formation, manchette organization, spermatid head morphogenesis and mitochondrial sheath assembly within the sperm flagellum during spermiogenesis (PubMed:34231842). Also required for proper assembly and stabilization of the C2a projection, a structural subunit of the central pair apparatus within the axoneme of motile cilia and flagella (PubMed:39853433)
Interacts with CFAP47 (PubMed:33472045). Interacts with MYCBPAP (PubMed:39092789, PubMed:39853433). Interacts with MNS1, TPPP2, RSPH1, ZPBP and SPACA1 (PubMed:34231842). Interacts with WDR35, SPAG16, SPATA4, CFAP20 and CFAP70 (PubMed:39853433). Interacts with MYCBP in a MYCBPAP-dependent manner (PubMed:39853433)
Cell projection, cilium, flagellum membrane, Cytoplasmic vesicle, secretory vesicle, acrosome membrane, Cytoplasm, Cell projection, cilium, flagellum, Cytoplasm, cytoskeleton, cilium axoneme, Cytoplasm, cytoskeleton, flagellum axoneme
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9IJJ | EM | 7.7 Å | h/i/j=1-1847 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.