Q4V3E2: Protein MRG2 (MRG2)

Protein MRG2 (MRG2) is a 327-residue protein from Arabidopsis thaliana. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q4V3E2.

Gene
MRG2
Organism
Arabidopsis thaliana
Length
327 residues
Mean pLDDT
74.2
Model
AF-Q4V3E2-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 74.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate34%
70 to 90Confident: backbone generally right32%
50 to 70Low: treat with caution10%
Below 50Very low: often disordered regions23%

What pLDDT means and how to read it

Function

Chromatin remodeling factor. Acts as a 'reader' protein by binding to H3K4me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed:25183522, PubMed:25211338). Binds the chromatin at the FT promoter upon interaction with CO (PubMed:25211338)

Subunit structure

Interacts with HAM1 and HAM2 (PubMed:25183522). Interacts (via MRG domain) with CO (PubMed:25211338). Component of the NuA4 histone acetyltransferase complex (By similarity)

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4PLIX-ray1.65 ÅA/B=51-123
4PL6X-ray1.68 ÅA/B=51-123
4PLLX-ray2.6 ÅA/B=51-123

More AlphaFold highlights

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