HLA class I antigen (HLA-A) is a 365-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q53Z42.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 85.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 10% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 15% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6TRN | X-ray | 1.35 Å | A=25-300 |
| 8FU4 | X-ray | 1.6 Å | A=25-299 |
| 7UM2 | X-ray | 1.63 Å | A=1-365 |
| 7U1R | X-ray | 1.8 Å | A=1-365 |
| 8RBV | X-ray | 1.8 Å | A=1-365 |
| 7RTD | X-ray | 2.05 Å | A=1-365 |
| 9MIN | X-ray | 2.05 Å | A/F=24-300 |
| 7UR1 | X-ray | 2.17 Å | A=1-365 |
| 7RTR | X-ray | 2.6 Å | A=1-365 |
| 8TBV | X-ray | 2.64 Å | A/D=25-299 |
| 6TRO | X-ray | 3.0 Å | A=25-300 |
| 6P64 | X-ray | 3.05 Å | A/F=25-299 |
| 8ESB | EM | 3.12 Å | A/B/C=25-303 |
| 8ESA | EM | 3.4 Å | A/B/C=25-303 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.