Protein cornichon homolog 2 (Cnih2) is a 160-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q5BJU5.
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The mean pLDDT of this model is 87.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 59% |
| 70 to 90 | Confident: backbone generally right | 29% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors
Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8 Interacts with CACGN8 (By similarity). Interacts with GRIA1. Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, DLG4 and CACNG8 (By similarity)
Endoplasmic reticulum membrane, Postsynaptic cell membrane, Cell projection, dendrite, Cell projection, dendritic spine, Postsynaptic density
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7OCE | EM | 3.1 Å | E/G=1-160 |
| 7OCA | EM | 3.4 Å | E/G=1-160 |
| 7OCF | EM | 3.6 Å | E/G=1-160 |
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