Q5SXM2: snRNA-activating protein complex subunit 4 (SNAPC4)

snRNA-activating protein complex subunit 4 (SNAPC4) is a 1469-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q5SXM2.

Gene
SNAPC4
Organism
Homo sapiens
Length
1469 residues
Mean pLDDT
51.6
Model
AF-Q5SXM2-F1 v6
Model created
1 Aug 2025
PDB structures
18

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Model confidence (pLDDT)

The mean pLDDT of this model is 51.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate10%
70 to 90Confident: backbone generally right22%
50 to 70Low: treat with caution13%
Below 50Very low: often disordered regions55%

What pLDDT means and how to read it

Function

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

Subunit structure

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC4 interacts with SNAPC1, SNAPC2, SNAPC5, BRF2 and TBP

Subcellular location

Nucleus

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7ZWDEM3.0 Åc=1-1469
7ZX8EM3.0 Åc=1-1469
9K3UEM3.0 Å4=1-1469
7ZWCEM3.2 Åc=1-1469
9FSOEM3.28 ÅW=2-1469
9LXNEM3.3 Å4=1-1469
9FSPEM3.39 ÅW=2-1469
7ZX7EM3.4 Åc=1-1469
8IUHEM3.4 Å4=1-1469
7XUREM3.49 ÅA=1-505
7ZXEEM3.5 Åc=1-1469
9K3VEM3.5 Å4=1-1469
9FSQEM3.51 ÅW=2-1469
9FSREM3.76 ÅW=2-1469
8ITYEM3.9 Å4=1-1469
8IUEEM4.1 Å4=1-1469
9FSSEM4.14 ÅW=2-1469
9K3BEM4.8 Å4=1-1469

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