Receptor-type tyrosine-protein phosphatase delta (Ptprd) is a 1912-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q64487.
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The mean pLDDT of this model is 82.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 32% |
| 70 to 90 | Confident: backbone generally right | 56% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically (PubMed:25908590). Involved in pre-synaptic differentiation through interaction with SLITRK2 (PubMed:25989451)
Interacts with PPFIA1, PPFIA2 and PPFIA3 (By similarity). Interacts (via extracellular domain) with SLITRK4 (via LRR 1 and 2 repeats) (PubMed:25989451). Interacts with SLITRK2; induces presynaptic differentiation (PubMed:25989451). Interacts (via the second immunoglobulin domain) with IL1RAPL1 (via the first immunoglobulin domain); induces pre- and postsynaptic differentiation of neurons and…
Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6KIP | X-ray | 1.91 Å | A=1617-1912 |
| 4YFE | X-ray | 1.97 Å | A/B=321-511 |
| 5Y32 | X-ray | 2.7 Å | A=21-318 |
| 5XWU | X-ray | 3.16 Å | A/C=20-321 |
| 4YFD | X-ray | 3.25 Å | A=21-511 |
| 4Y61 | X-ray | 3.36 Å | A=21-411 |
| 4YFG | X-ray | 3.49 Å | A/B=21-511 |
| 7CEG | X-ray | 3.85 Å | A=21-411 |
| 5XWT | X-ray | 4.18 Å | A/C=20-410 |
| 4YH7 | X-ray | 4.4 Å | A=21-1265 |
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