Genome polyprotein is a 22-residue protein from Human enterovirus D68. This is its AlphaFold structure prediction, created 3 Jul 2025. UniProt accession: Q68T42.
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The mean pLDDT of this model is 67.5 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 23% |
| 50 to 70 | Low: treat with caution | 77% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Component of immature procapsids, which is cleaved into capsid proteins VP4 and VP2 after maturation (By similarity). Allows the capsid to remain inactive before the maturation step (By similarity)
Interacts with capsid protein VP1 and capsid protein VP3 to form heterotrimeric protomers
Virion, Host cytoplasm, Host mitochondrion, Host cytoplasmic vesicle membrane, Host nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7GPX | X-ray | 1.2 Å | A/B=1548-1729 |
| 7GPV | X-ray | 1.23 Å | A/B=1548-1729 |
| 7GPA | X-ray | 1.25 Å | A/B=1548-1729 |
| 7GOW | X-ray | 1.28 Å | A/B=1548-1729 |
| 7GPF | X-ray | 1.28 Å | A/B=1548-1729 |
| 7GQ7 | X-ray | 1.28 Å | A/B=1548-1729 |
| 7GOQ | X-ray | 1.3 Å | A/B=1548-1729 |
| 7GP7 | X-ray | 1.3 Å | A/B=1548-1729 |
| 7GPI | X-ray | 1.3 Å | A/B=1548-1729 |
| 7GQG | X-ray | 1.3 Å | A/B=1548-1729 |
| 7GP2 | X-ray | 1.31 Å | A/B=1548-1729 |
| 7GPG | X-ray | 1.31 Å | A/B=1548-1729 |
| 7GPC | X-ray | 1.32 Å | A/B=1548-1729 |
| 7GQ1 | X-ray | 1.32 Å | A/B=1548-1729 |
| 7GO2 | X-ray | 1.34 Å | A/B=1548-1729 |
| 7GOV | X-ray | 1.34 Å | A/B=1548-1729 |
| 7GQF | X-ray | 1.34 Å | A/B=1548-1729 |
| 7GP8 | X-ray | 1.35 Å | A/B=1548-1729 |
| 7GQ2 | X-ray | 1.35 Å | A/B=1548-1729 |
| 7GQB | X-ray | 1.35 Å | A/B=1548-1729 |
Showing 20 of 121 experimental structures (best resolution first).
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