Cell division cycle-associated protein 2 (CDCA2) is a 1023-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q69YH5.
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The mean pLDDT of this model is 46.2 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 1% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 15% |
| Below 50 | Very low: often disordered regions | 77% |
What pLDDT means and how to read it
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phosphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates
Interacts with PPP1CC
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5INB | X-ray | 1.3 Å | B=383-423 |
| 5IOH | X-ray | 2.57 Å | B/D=383-441 |
| 5SW9 | X-ray | 2.85 Å | B=581-601 |
| 5D1Z | X-ray | 3.17 Å | I/J=670-723, I/J=727-737 |
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