Q6PH85: DCN1-like protein 2 (DCUN1D2)

DCN1-like protein 2 (DCUN1D2) is a 259-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q6PH85.

Gene
DCUN1D2
Organism
Homo sapiens
Length
259 residues
Mean pLDDT
93.8
Model
AF-Q6PH85-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 93.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate90%
70 to 90Confident: backbone generally right7%
50 to 70Low: treat with caution1%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and plays an essential role in the regulation of SCF (SKP1-CUL1-F-box protein)-type complexes activity

Subunit structure

Interacts (via the DCUN1 domain) with the unneddylated cullins: interacts with CUL1, CUL2, CUL3, CUL4A, CUL4B and CUL5; these interactions promote the cullin neddylation and the identity of the cullin dictates the affinity of the interaction (PubMed:19617556, PubMed:23201271, PubMed:26906416). May also interact with regulators or subunits of cullin-RING ligases such as RBX1, RNF7, ELOB and DDB1;…

Subcellular location

Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4GAOX-ray3.28 ÅA/B/D/G=62-259

More AlphaFold highlights

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