IGK@ protein (IGK@) is a 236-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q6PIL8.
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The mean pLDDT of this model is 92.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6E56 | X-ray | 2.0 Å | I/J=21-236 |
| 6UDJ | EM | 2.5 Å | E/I/O=7-236 |
| 6BKB | X-ray | 2.8 Å | L=21-236 |
| 1U6A | X-ray | 2.81 Å | L=21-236 |
| 3HI1 | X-ray | 2.9 Å | A/L=21-236 |
| 7B0B | X-ray | 2.98 Å | L=21-236 |
| 6V8X | EM | 3.0 Å | D/H/L=23-236 |
| 4OQT | X-ray | 3.23 Å | L=24-236 |
| 6BKD | X-ray | 3.25 Å | L=24-236 |
| 5UG0 | X-ray | 3.4 Å | C=21-236 |
| 5W1K | X-ray | 3.99 Å | C/H/M/N=23-235 |
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