IGK@ protein (IGK@) is a 235-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q6PJF2.
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The mean pLDDT of this model is 92.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 87% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8QH0 | X-ray | 1.87 Å | L=21-234 |
| 1DN0 | X-ray | 2.28 Å | A/C=21-234 |
| 2AGJ | X-ray | 2.6 Å | L=21-235 |
| 8QH1 | X-ray | 2.65 Å | L=21-235 |
| 1QLR | X-ray | 2.83 Å | A/C=21-234 |
| 4YPG | X-ray | 3.0 Å | A/L=21-235 |
| 6MYY | EM | 3.8 Å | C/F/L=7-235 |
| 6UDK | EM | 3.9 Å | E/L/N=7-235 |
| 6MZJ | EM | 4.8 Å | C/L=7-235 |
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