Proton-gated ion channel (glvI) is a 359-residue protein from Gloeobacter violaceus (strain ATCC 29082 / PCC 7421). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7NDN8.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 89.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change
Homopentamer
Cell inner membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9LBD | EM | 2.14 Å | A/B/C/D/E=47-358 |
| 6HZW | X-ray | 2.22 Å | A/B/C/D/E=43-359 |
| 3IGQ | X-ray | 2.3 Å | A/B/C/D/E/F=44-235 |
| 6F0U | X-ray | 2.35 Å | A/B/C/D/E=43-359 |
| 4HFI | X-ray | 2.4 Å | A/B/C/D/E=44-359 |
| 6F0R | X-ray | 2.5 Å | A/B/C/D/E=43-359 |
| 6F0Z | X-ray | 2.5 Å | A/B/C/D/E=43-359 |
| 6HJZ | X-ray | 2.5 Å | A/B/C/D/E/F/G/H/I/J=43-359 |
| 6HZ1 | X-ray | 2.5 Å | A/B/C/D/E=44-359 |
| 6HY5 | X-ray | 2.58 Å | A/B/C/D/E=47-357 |
| 3TLW | X-ray | 2.6 Å | A/B/C/D/E=44-359 |
| 5IUX | X-ray | 2.6 Å | A/B/C/D/E=43-359 |
| 6F16 | X-ray | 2.6 Å | A/B/C/D/E=43-359 |
| 4HFH | X-ray | 2.65 Å | A/B/C/D/E=44-359 |
| 5MZR | X-ray | 2.65 Å | A/B/C/D/E=43-359 |
| 5MZT | X-ray | 2.65 Å | A/B/C/D/E=43-359 |
| 6F0M | X-ray | 2.65 Å | A/B/C/D/E=43-359 |
| 8JJ3 | EM | 2.65 Å | A/B/C/D/E=47-358 |
| 6F13 | X-ray | 2.7 Å | A/B/C/D/E=43-359 |
| 6HJ3 | X-ray | 2.7 Å | A/B/C/D/E=43-359 |
Showing 20 of 130 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.