NAD(+)--protein-threonine ADP-ribosyltransferase (cteC) is a 276-residue protein from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG 213 / NBRC 12614 / NCIMB 9131 / NCTC 9757 / MK). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7NY09.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 43.3 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 23% |
| Below 50 | Very low: often disordered regions | 67% |
What pLDDT means and how to read it
ADP-ribosyltransferase that specifically modifies host ubiquitin on 'Thr-66' residue, which causes the shutdown of polyubiquitin synthesis and disrupts the recognition and reversal of polyubiquitin in host cells during infection (PubMed:32330457). Threonine ADP-ribosylation of ubiquitin prevents the transfer of ubiquitin from ubiquitin-activating enzyme E1 to ubiquitin-conjugating enzyme E2, which inhibits subsequent ubiquitin activation and leads to the shutdown of polyubiquitin synthesis in host cells (PubMed:32330457). The modification also causes dysfunction of polyubiquitin chains in cells, thereby blocking host ubiquitin signaling (PubMed:32330457). ADP-ribosylation by CteC is likely…
Interacts directly with host ubiquitin
Secreted, Host cell
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8HTD | X-ray | 1.85 Å | A=45-276 |
| 8UX2 | X-ray | 1.87 Å | A/B/C=36-276 |
| 8HTF | X-ray | 2.15 Å | A=45-276 |
| 8HTC | X-ray | 2.2 Å | A=45-276 |
| 8HTE | X-ray | 2.31 Å | A=45-276 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.