Protein prenyltransferase alpha subunit repeat-containing protein 1 (PTAR1) is a 402-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7Z6K3.
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The mean pLDDT of this model is 83.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 69% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 15% |
What pLDDT means and how to read it
Substrate-recognition subunit of the geranylgeranyl transferase type 3 (GGTase-3) complex (PubMed:31209342, PubMed:32128853). The GGTase-3 complex geranylgeranylates and targets FBXL2 to the cellular membranes, where FBXL2 forms part of the E3 ubiquitin-protein ligase complex SCF(FBXL2) that mediates the degradation of membrane-anchored proteins (PubMed:31209342, PubMed:32128853). The GGTase-3 complex geranylgeranylates Golgi v-SNARE protein YKT6 at 'Cys-194' and this prenylation is required for Golgi SNARE complex assembly (PubMed:32128853)
Part of the GGTase-3 complex, composed of PTAR1 and RABGGTB; this complex geranylgeranylates FBXL2 and YKT6
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6O60 | X-ray | 2.5 Å | A=1-402 |
| 6J7X | X-ray | 2.75 Å | A=1-327 |
| 6J7F | X-ray | 2.88 Å | A=1-327 |
| 6J6X | X-ray | 2.96 Å | A=1-339 |
| 6J74 | X-ray | 3.21 Å | A=1-327 |
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