Q82122: Genome polyprotein

Genome polyprotein is a 166-residue protein from Human rhinovirus 16. This is its AlphaFold structure prediction, created 3 Jul 2025. UniProt accession: Q82122.

Organism

Human rhinovirus 16

Length

166 residues

Mean pLDDT

95.8

Model

AF-0000000365760811 v1

Model created

3 Jul 2025

PDB structures

13

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Model confidence (pLDDT)

The mean pLDDT of this model is 95.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

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Function

Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3 (By similarity). The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome (By similarity). Capsid protein VP1 mainly forms the vertices of the capsid (By similarity). Capsid protein VP1 interacts with host cell receptor to provide virion attachment to target host cells (By similarity). This attachment induces virion internalization (By similarity). Tyrosine kinases are probably involved in the entry process (By similarity). After binding to its receptor, the capsid undergoes conformational changes (By similarity). Capsid protein…

Subunit structure

Interacts with capsid protein VP1 and capsid protein VP3 to form heterotrimeric protomers

Subcellular location

Virion, Host cytoplasm, Host cytoplasmic vesicle membrane, Host nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

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