MHC class I antigen (HLA-A) is a 341-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q861F7.
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The mean pLDDT of this model is 88.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 78% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 9% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7KGQ | X-ray | 1.34 Å | A=1-278 |
| 7KGP | X-ray | 1.4 Å | A=1-278 |
| 7KGR | X-ray | 1.55 Å | A=1-278 |
| 7KGS | X-ray | 1.58 Å | A=1-278 |
| 7T5M | X-ray | 1.67 Å | A/C=1-278 |
| 7PDW | X-ray | 1.82 Å | CCC/HHH=1-276 |
| 7KGT | X-ray | 1.9 Å | A=1-278 |
| 7SIS | X-ray | 1.9 Å | A=1-277 |
| 7PBC | X-ray | 2.04 Å | CCC=1-276 |
| 7KGO | X-ray | 2.15 Å | A=1-278 |
| 8ES8 | EM | 2.65 Å | N=1-276 |
| 8FJA | EM | 3.0 Å | A=1-276 |
| 8FJB | EM | 3.06 Å | A=1-276 |
| 8ES9 | EM | 3.25 Å | N=1-276 |
| 9NNF | EM | 3.8 Å | B=1-276 |
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