B-cell CLL/lymphoma 9-like protein (BCL9L) is a 1499-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q86UU0.
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The mean pLDDT of this model is 42.2 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 2% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 87% |
What pLDDT means and how to read it
Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity)
Found in a complex with CDC73; CTNNB1 and PYGO1. Interacts with CTNNB1
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4UP0 | X-ray | 1.28 Å | A=240-268 |
| 4UP5 | X-ray | 1.65 Å | A=240-268 |
| 2XB1 | X-ray | 1.9 Å | A/C=224-271 |
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