Early protein OPG038 (CPXV040 CDS) is a 220-residue protein from Cowpox virus. This is its AlphaFold structure prediction, created 3 Jul 2025. UniProt accession: Q8QN22.
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The mean pLDDT of this model is 75.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 27% |
| 70 to 90 | Confident: backbone generally right | 39% |
| 50 to 70 | Low: treat with caution | 20% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Plays a role in immune evasion. When secreted, inhibits T-cell activation by preventing the binding of host CD80 and CD86 to soluble CTLA4 and CD28. In the infected cell, may inhibit host NF kappa B activation
Homooligomer. Interacts with host CD80 and CD86 when secreted
Host endoplasmic reticulum, Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8FXW | EM | 2.7 Å | A/B/D/F/I/K=18-220 |
| 8FXZ | EM | 2.86 Å | A/B/D/F/I/K/M=18-220 |
| 8FXX | EM | 3.26 Å | A/B/D/F/I/K/M=18-218 |
| 8FXY | EM | 3.34 Å | A/B/D/F/I/K=18-218 |
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