Serine/threonine-protein kinase haspin (HASPIN) is a 798-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8TF76.
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The mean pLDDT of this model is 62.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 40% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 53% |
What pLDDT means and how to read it
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle
Nucleus, Chromosome, Cytoplasm, cytoskeleton, spindle
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4QTC | X-ray | 1.4 Å | A=465-798 |
| 6G3A | X-ray | 1.43 Å | A=465-798 |
| 6G39 | X-ray | 1.45 Å | A=465-798 |
| 6G36 | X-ray | 1.46 Å | A=465-798 |
| 6G38 | X-ray | 1.47 Å | A=465-798 |
| 6G37 | X-ray | 1.48 Å | A=465-798 |
| 5HTC | X-ray | 1.5 Å | A=465-798 |
| 6Z57 | X-ray | 1.5 Å | A=465-798 |
| 6Z5E | X-ray | 1.5 Å | A=465-798 |
| 6G35 | X-ray | 1.55 Å | A=465-798 |
| 6Z5A | X-ray | 1.55 Å | A=465-798 |
| 7AVQ | X-ray | 1.65 Å | A=465-798 |
| 5HTB | X-ray | 1.7 Å | A=465-798 |
| 6Z5C | X-ray | 1.75 Å | A=465-798 |
| 6Z5D | X-ray | 1.75 Å | A=465-798 |
| 6G34 | X-ray | 1.76 Å | A=465-798 |
| 7SQM | X-ray | 1.78 Å | A=445-798 |
| 2VUW | X-ray | 1.8 Å | A=465-798 |
| 3F2N | X-ray | 1.8 Å | A=465-798 |
| 6Z58 | X-ray | 1.8 Å | A=465-798 |
Showing 20 of 41 experimental structures (best resolution first).
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