Q8VDC1: FYVE and coiled-coil domain-containing protein 1 (Fyco1)

FYVE and coiled-coil domain-containing protein 1 (Fyco1) is a 1437-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8VDC1.

Gene
Fyco1
Organism
Mus musculus
Length
1437 residues
Mean pLDDT
72.6
Model
AF-Q8VDC1-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 72.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate17%
70 to 90Confident: backbone generally right52%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions19%

What pLDDT means and how to read it

Function

May mediate microtubule plus end-directed vesicle transport

Subunit structure

Can form homodimers. Interacts (via C-terminus) with MAP1LC3B. Interacts with RAB7A; the interaction with RAB7A induces FYCO1 recruitment to late endosomal/lysosomal compartments

Subcellular location

Cytoplasmic vesicle, autophagosome, Endosome, Lysosome

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5WRDX-ray1.9 ÅC/D=1235-1253

More AlphaFold highlights

About this viewer

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